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Part Two is an exhaustive scientific background, comprised of 16 landmark studies, describing its advantages for selected foot and ankle injuries and deformities (both congenital and acquired). With this science as context, Part Three includes chapters on the technical aspects and necessary background for WBCT, introduces the different devices, and provides insight into the actual measurement possibilities, including the initial software solutions for automatic measurements. Current clinical applications via case material are illustrated in atlas-like fashion in the next chapter, and a final chapter on future developments explores further applications of WBCT, such as dynamic scans and measurements or hologram-like visualization. The first book publication of its kind on this exciting and developing imaging modality, Weight Bearing Cone Beam Computed Tomography (WBCT) in the Foot and Ankle will be an excellent resource for orthopedic and foot and ankle surgeons, radiologists, and allied medical professionals working in this clinical area.\u003c\/p\u003e","brand":"Gardners","offers":[{"title":"Default Title","offer_id":52915431473431,"sku":null,"price":9447.07,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0679\/6918\/8119\/files\/9783030319496.jpg?v=1781526854"},{"product_id":"targeted-therapy-of-colorectal-cancer-subtypes-9783030027711","title":"Targeted Therapy of Colorectal Cancer Subtypes","description":"\u003cp\u003eColorectal cancer (CRC) is a leading cause of cancer-related death worldwide. Recent years have increased significantly our understanding of the genetic alterations that can underlie CRC, but also unraveled the molecular heterogeneity of the disease. 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Importantly, the data accumulated in recent years  such as anisotropic stiffness, elastic engineering moduli, compression and shear wave speeds of cortical bones from various skeletal sites are presented comprehensively. A few chapters deal with the recent developments achieved in quantitative ultrasound of trabecular bone. These include (i) scattering-based approaches and their application to measure skeletal sites such as the spine and proximal femur and (ii) approaches exploiting the poro-elastic nature of bone. While bone fragility and osteoporosis are still the main motivation for developing bone QUS, this Book also includes chapters reporting ultrasound techniques developed for other applications of high interest such as 3-D imaging of the spine, assessment of implant stability and transcranial brain imaging.This book, together with the book ‘Bone Quantitative Ultrasound’ published in 2011 will provide a comprehensive overview of the methods and principles used in bone quantitative ultrasound and will be a benchmark for all novice or experienced researchers in the field. The book will offer recent experimental results and theoretical concepts developed so far and would be intended for researchers, graduate or undergraduate students, engineers, and clinicians who are involved in the field. The book should be considered as a complement to the first book publisher in 2011, rather than a second edition, in the sense that basic notions already presented in the first book are not repeated.\u003c\/p\u003e","brand":"Gardners","offers":[{"title":"Default Title","offer_id":52915589349655,"sku":null,"price":18829.37,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0679\/6918\/8119\/files\/9783030919795.jpg?v=1781527481"},{"product_id":"advances-in-computer-vision-and-computational-biology-9783030710514","title":"Advances in Computer Vision and Computational Biology","description":"\u003cp\u003eThe book presents the proceedings of four conferences: The 24th International Conference on Image Processing, Computer Vision, \u0026amp; Pattern Recognition (IPCV''20), The 6th International Conference on Health Informatics and Medical Systems (HIMS''20), The 21st International Conference on Bioinformatics \u0026amp; Computational Biology (BIOCOMP''20), and The 6th International Conference on Biomedical Engineering and Sciences (BIOENG''20). 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Primarily intended for healthcare workers in The Gambia and other nations with a similar socio-economical background, the book is also a valuable resource for international students and healthcare workers from regions like Europe and the Americas intending to do internships in economically underprivileged geographic areas.\u003c\/p\u003e","brand":"Gardners","offers":[{"title":"Default Title","offer_id":52915593445655,"sku":null,"price":12080.49,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0679\/6918\/8119\/files\/9783030710323.jpg?v=1781527584"},{"product_id":"role-of-glycosylation-in-health-and-disease-9783030701154","title":"Role of Glycosylation in Health and Disease","description":"\u003cp\u003eGlycobiology is an emerging field of studying glycans (sugars) and glycoconjugates that are essentially involved in almost all biological processes, from fine-tuning glycoprotein function to protein-protein interactions, signaling, immune response, host-pathogen interactions, etc. However, due to structural complexity of glycans and analytical challenges this exciting field was lagging behind other areas of biology. 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A total of 140 papers were submitted to the conference, but only 111 papers were published in this book. 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The information contained in the book explores different areas of machine and deep learning, advanced image processing, computational intelligence, IoT, robotics and automation, optimization, mathematical modeling, neural networks, information technology, big data, data processing, data mining, and likewise. Moreover, the chapters include the theory and methodologies used to provide an overview of applying these tools to the useful contribution to help to face the emerging disaster. The book is primarily intended for researchers, decision makers, practitioners, and readers interested in these subject matters. 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There is still relatively little published on the technical and scientific principles on routine tissue and cell banking based on scientific principles. The 1st edition was very successful and, after a 10 year gap, there is a need of an update and an expansion of the book’s remit. The format of the book follows that of the previous edition- split into 5 sections. Management of donors and the banking of common tissues and cells; Principles of storage and processing of tissues and cells; Ensuring the safety of the products by testing the donor, the tissues and the environment, supported by a quality system and an IT infrastructure- all working within the constraints of current regulatory and ethical environments. This edition however provides a significant update. Many the chapters have been completely rewritten by different experts. Like the 1st edition, they were given a free hand in the way they wrote their chapter, with a guideline that they had to be concise, clear and up to date. The authors were also asked to provide the scientific and technical basis that provides the rationale of the processes they describe. Also, the scope of the book has been somewhat extended. In view of the fact that many cellular therapies are now routinely practiced, 2 new chapters have been added: one on the banking of haematopoietic stem cells and one on human embryonic stem cells. They have been deliberately chosen to illustrate the extreme spectrum of cellular therapies from one of the simplest to one of the most complex.  The intention of the book has remained the same: to cover and update banking of current practices in essential tissue and cell banking. It is therefore hoped that by keeping the book as concise and up to date as possible, it will find a place on the shelves of many tissueestablishments.\u003c\/p\u003e","brand":"Gardners","offers":[{"title":"Default Title","offer_id":52915599212823,"sku":null,"price":16129.82,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0679\/6918\/8119\/files\/9783030716219.jpg?v=1781527686"},{"product_id":"career-development-in-academic-radiation-oncology-9783030718558","title":"Career Development in Academic Radiation Oncology","description":"\u003cp\u003eThis book offers comprehensive career development advice for professionals in radiation oncology. While numerous texts have been published to advise medical students on entry into the specialty, and to guide residents and junior faculty with exam preparation, there remains a need for a comprehensive resource that covers topics pertinent to a successful career within radiation oncology. This text has been edited and written by leading experts in the field, and offers multiple unique vantage points. This work is divided into five sections covering career planning, applying to faculty positions, early career development, mid and senior career considerations, and contextual issues. Throughout the text, authors balance “nuts and bolts” (e.g., preparing your CV and evaluating a contract) with big picture considerations. Each chapter is written concisely, yet comprehensively, from the vantage point of a mentor advising a mentee; questions to review with local mentors and additional reading suggestions are also provided. Issues of workforce disparities, conscious and unconscious bias, work-life equilibrium, and interpersonal conflict, and how these may impact one’s career path, are also closely addressed. While the work is primarily targeted to those pursuing career paths within academic medicine, there is also distinct value and tailored content for trainees and radiation oncologists practicing in hospital-based, hybrid or community settings. In a period of rapid change in the healthcare sector and cancer care more specifically, this book will serve as the premier reference for those pursuing an independent career in radiation oncology.\u003c\/p\u003e","brand":"Gardners","offers":[{"title":"Default Title","offer_id":52915600556311,"sku":null,"price":14780.04,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0679\/6918\/8119\/files\/9783030718558.jpg?v=1781527728"},{"product_id":"cell-biology-and-translational-medicine-volume-12-9783030719333","title":"Cell Biology and Translational Medicine, Volume 12","description":"\u003cp\u003eMuch research has focused on the basic cellular and molecular biological aspects of stem cells. Much of this research has been fueled by their potential for use in regenerative medicine applications, which has in turn spurred growing numbers of translational and clinical studies. However, more work is needed if the potential is to be realized for improvement of the lives and well-being of patients with numerous diseases and conditions. This book series ''Cell Biology and Translational Medicine (CBTMED)'' as part of Springer Nature’s long-standing and very successful Advances in Experimental Medicine and Biology book series, has the goal to accelerate advances by timely information exchange. Emerging areas of regenerative medicine and translational aspects of stem cells are covered in each volume. Outstanding researchers are recruited to highlight developments and remaining challenges in both the basic research and clinical arenas. 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These were held jointly at the 23rd Medical Image Computing for Computer Assisted Intervention Conference, MICCAI 2020, in Lima, Peru, in October 2020.* The revised selected papers presented in these volumes were organized in the following topical sections: brain lesion image analysis (16 selected papers from 21 submissions); brain tumor image segmentation (69 selected papers from 75 submissions); and computational precision medicine: radiology-pathology challenge on brain tumor classification (6 selected papers from 6 submissions). *The workshop and challenges were held virtually.\u003c\/p\u003e","brand":"Gardners","offers":[{"title":"Default Title","offer_id":52915600851223,"sku":null,"price":13430.27,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0679\/6918\/8119\/files\/9783030720841.jpg?v=1781527737"},{"product_id":"transradial-access-in-interventional-radiology-9783030816780","title":"Transradial Access in Interventional Radiology","description":"\u003cp\u003eThis book provides how-to recommendations and detailed guides for using transradial access in interventional radiology. A relatively new and growing technique, transradial access is most commonly found within interventional cardiology. This book approaches those cardiac uses of transradial access while extending its use to other body sites and disease states. The book details the interventional radiologist’s transition to using transradial access across a broad spectrum of clinical applications, allowing them to better introduce it into their practice and to their patients.  The text is divided into three sections: overview, clinical applications, and novel applications and techniques. The first section covers the history of transradial access, the initial patient assessment, and how to prepare for a procedure. The second section is divided into different diseases and interventional situations where transradial access could be considered, including subclavian artery stenosis and endovascular neurosurgery. The third section includes coverage of how to perform the latest techniques and projections for future procedures. This guide provides a manual of operations to assist in the setup of the practice, from office visit to procedure room to recovery across a variety of service lines and patient populations. Key take home points and equipment summaries accompany each chapter, allowing the user to easily navigate the book to accelerate his or her practice. 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Finally, a special chapter on state-of-the-art technologies helps the reader not only to understand epigenetic driven changes in human cognition and diseases but also the methodology that will help to generate paradigm shifts on our understanding of brain function and the role of the neuroepigenome in human diseases.\u003c\/p\u003e","brand":"Gardners","offers":[{"title":"Default Title","offer_id":52915614613783,"sku":null,"price":21528.92,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0679\/6918\/8119\/files\/9783319538891.jpg?v=1781528341"},{"product_id":"understanding-cancer-9783030973933","title":"Understanding Cancer","description":"\u003cp\u003eThis book provides a unique, wide-ranging description of the phenomenon of cancer and its pathological effects in diverse species including humans, domesticated and wild animals, invertebrates, and plants. The broad scope of information presented is used to construct radical new insights into biological self-regulation and explain their relevance to its disruption by cancerous growth and spread within the human body. Mechanisms of action of carcinogenic agents, initiation, progression, metastasis, inappropriate gene expression, dormancy, latency, regression, and reasons for susceptibility and\/or resistance to cancer are all considered. Also discussed are criteria for pathological diagnosis, advances in treatment, implications for public health, and pitfalls in diagnosis and interpretation of experimental results. The book describes operational mechanisms of cancer at the levels of whole individual, organ, tissue, cell, molecular, and even atomic (quantum) scales of structural and physiological order.  Evidence is assembled from all these levels of organization to show that cancer is a dynamically changing disorder and that it is an inherent and perpetual risk of multicellular composition. This provides pragmatic new biological and clinical perspectives on malignant neoplasia.  The biological insight is that it is a consequence of progressing miscommunication within a cellular society. The clinical perspective is realistic but optimistic in reasoning that, although cancer can never be completely eradicated from human life, because it is a disorder of our intrinsic biological constitution, it can be controlled and ameliorated and even cured in a proportion of individuals. The text is profusely illustrated with over 300 macroscopic and microscopic pictures. It will stimulate curiosity and interest specialists, as well as beginners, in many scientific disciplines and provides copiousreferences to the medical and scientific literature supporting its conclusions. Readers from fields as diverse as medicine, pathology, veterinary sciences, cell biology, molecular biology, developmental biology, and epidemiology will find the information the book contains thought-provoking, interesting, and useful. 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Further coverage includes comparisons to traditional probiotics, as well as probiotic safety and side-effects. Metabiotics: Present State, Challenges and Perspectives provides a complete history and understanding of this new field, the next phase of the probiotic industry.\u003c\/p\u003e","brand":"Gardners","offers":[{"title":"Default Title","offer_id":52915629555991,"sku":null,"price":20111.65,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0679\/6918\/8119\/files\/9783030341671.jpg?v=1781528855"},{"product_id":"musculoskeletal-ultrasound-in-orthopedic-and-rheumatic-disease-in-adults-9783030912024","title":"Musculoskeletal Ultrasound in Orthopedic and Rheumatic disease in Adults","description":"\u003cp\u003eThis book presents the major advances and technological updates in diagnostic ultrasound procedures, focusing on the principal technological aspects and multiple exam procedures for the pertinent anatomy, both under basal conditions and using Doppler techniques. 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Providing outstanding diagrams, dynamic images and videos to guide readers, it is a valuableresource for radiologists and clinicians (rheumatologists, orthopedists, physiatrists and anesthesiologists) with different levels of experience — ranging from physicians in training to those who already perform US examinations and US-guided procedures.\u003c\/p\u003e","brand":"Gardners","offers":[{"title":"Default Title","offer_id":52915639943447,"sku":null,"price":12080.49,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0679\/6918\/8119\/files\/9783030912024.jpg?v=1781528922"},{"product_id":"biochemistry-of-drug-resistance-9783030763206","title":"Biochemistry of Drug Resistance","description":"\u003cp\u003eThis book provides a comprehensive discussion on the current information and evidence on the latest developments in the field of drugs resistance. 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Therefore, there is an immense need for a systematic compilation on the available information about this issue.  All the chapters are logically selected and arranged to provide state-of-the-art information about all aspects of drugs resistance. After an introductory chapter, four chapters are dedicated to infectious microbial diseases, whereas two other chapters are complimenting this theme and focusing on drugs resistance in ear, nose and throat, and skin diseases. The recent advances in the understanding of drugs resistance in lung, neurological, kidney, heart, and liver diseases are also covered. Biochemistry of drugs resistance in cancer, HIV, ocular, reproductive, and diabetes diseases is also discussed. 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New cell-surface proteins and glycoproteins, which act as Collectin receptors, are currently being identified. Some Collectins, particularly MBL, activate the complement system, which enhances the ability of antibodies to fight pathogens, via three MBL-associated proteases, the MASPs. Additionally, recent research has begun to show wider-ranging activities of Collectins, such as:  ·         Their role in metabolism, and therefore their involvement in lifestyle diseases such as obesity and cardiovascular disease. ·        Their ability to modulate the adaptive immune response, as well as to recognize and trigger apoptosis of cancer cells, which makes them effective in the annihilation of cancer cells with multiple mutations.·         The regulation of their expression by gonadal steroid hormones implicates them with critical roles in both male and female fertility. ·         Altered levels of Collectins have been associated with various autoimmune diseases. 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The book provides a multimodality review of more than 300 commonly utilized radiologic signs in radiography, CT, MRI, US, angiography, and nuclear medicine, including PET-CT. It is designed to enhance recognition of specific imaging patterns and enable the image interpreter to confidently reach an accurate diagnosis. Divided into ten chapters dedicated to different anatomic areas, each sign includes detailed discussion that explains the history and meaning of the descriptive or metaphoric sign, alongside illustrative photos for memory aid andclarification. Uniquely written from a practical point of view, each case leads you through a radiology expert’s thought process in analyzing the classic signs with considerations of common misinterpretations and imaging pitfalls. The cases then highlight clinical presentation, relevant pathology, anatomy, physiology, and pertinent imaging features of common disease processes. Key information is distilled into succinct, bulleted points with detailed illustrations and images. This book is an ideal reference and review for practicing radiologists, as well as trainees preparing for licensing examinations.\u003c\/p\u003e","brand":"Gardners","offers":[{"title":"Default Title","offer_id":52915682050327,"sku":null,"price":13430.27,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0679\/6918\/8119\/files\/9783030563486.jpg?v=1781529025"},{"product_id":"vasoplegic-endothelial-dysfunction-9783030740962","title":"Vasoplegic Endothelial Dysfunction","description":"\u003cp\u003eThis unique work presents one of the most significant organ failure condition – cardiocirculatory shock – and the prominent role of Methylene Blue (MB). Through their extensive experience, the authors’ consider that the lifesaving feature of MB is still underestimated. For this reason they outline key concepts of MB, mentioning essential experimental data, yet focusing mainly on its application in the care of critically ill patients. In an easy-to-read format, the 18 chapters were organized in a didactically structured order, distributed in four parts. The first part introduces the general conceptual aspects and physiology of the endothelium. The second part presents the particularities of endothelial dysfunction in different types of shock. Methylene blue is discussed in detail in the third part. In the fourth part, particular situations of endothelial dysfunction, such as heart surgery and organ transplantation, are described. Additionally, the two complementary subjects of acid-base balance and the therapeutic use of inhaled nitric oxide are mentioned. Finally, looking for therapeutic alternatives for what we classify as \"vasoplegic endothelial dysfunction\", MB remains promising as an adjuvant to sympathomimetic amines. The combination of three recently proposed concepts may be useful in obtaining better results against the high mortality rates in critically ill patients. These three concepts are \"wide-spectrum vasopressors\", vasopressor economy strategies, and microcirculation protection against the harmful effects of using high concentrations of amines. 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This preclinical tool is extensively being utilised as a model for studying human diseases in a dish, which is critical for accurate predictive modelling in precision medicine. The chapters in this book introduces readers to the numerous applications of organoids in various fields of study, as well as ethical considerations associated with organoids. In stem cell biology and regenerative medicine, where chimaera research, biomaterials for tissue vascularisation, gene-editing technologies, and their use in clinical procedures especially issues related to ethical concern over the use of human organoids have gotten much attention. Organoid Technology for DiseaseModelling and Personalised Treatment is an excellent resource for in-depth research on one of the most interesting and significant topics in stem cell and regenerative medicine. This book''s chapter collection covers a fresh viewpoint on organoid technology that scholars will require reading.\u003c\/p\u003e","brand":"Gardners","offers":[{"title":"Default Title","offer_id":52915690275095,"sku":null,"price":18829.37,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0679\/6918\/8119\/files\/9783030930561.jpg?v=1781529237"},{"product_id":"efficient-data-handling-for-massive-internet-of-medical-things-9783030666330","title":"Efficient Data Handling for Massive Internet of Medical Things","description":"\u003cp\u003eThis book focuses on recent advances and different research areas in multi-modal data fusion under healthcare informatics and seeks out theoretical, methodological, well-established and validated empirical work dealing with these different topics. This book brings together the latest industrial and academic progress, research, and development efforts within the rapidly maturing health informatics ecosystem. Contributions highlight emerging data fusion topics that support prospective healthcare applications. The book also presents various technologies and concerns regarding energy aware and secure sensors and how they can reduce energy consumption in health care applications. It also discusses the life cycle of sensor devices and protocols with the help of energy-aware design, production, and utilization, as well as the Internet of Things technologies such as tags, sensors, sensing networks, and Internet technologies.  In a nutshell, this book gives a comprehensive overview of thestate-of-the-art theories and techniques for massive data handling and access in medical data and smart health in IoT, and provides useful guidelines for the design of massive Internet of Medical Things.\u003c\/p\u003e","brand":"Gardners","offers":[{"title":"Default Title","offer_id":52915691520279,"sku":null,"price":16129.82,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0679\/6918\/8119\/files\/9783030666330.jpg?v=1781529270"},{"product_id":"developing-and-utilizing-digital-technology-in-healthcare-for-assessment-and-monitoring-9783030606978","title":"Developing and Utilizing Digital Technology in Healthcare for Assessment and Monitoring","description":"\u003cp\u003eThis book discusses the current trends in nursing and healthcare in relation to the integration of information technological interventions across the care continuum. The use of such interventions in healthcare has increased rapidly in recent years, partly due to the rise in technological gadgets\/applications used in daily routines (e.g. actigraphy bracelets, smartphones) and their unique properties that can be utilized in assessing, monitoring and managing a patient’s condition remotely. This book highlights the areas and the ways in which these interventions can facilitate patient assessment and monitoring and complement conventional treatments in the management of disease-induced or treatment-induced side effects. Furthermore, the book describes the development of such interventions and examines how they are designed to promote adherence and acceptance by the user. To this end, the book also discusses the need for personalizing the technological experience according tothe user’s preferences and needs. Drawing on the latest studies in these areas, it not only provides suggestions for undertaking research in this context, but also offers insights into how these technologies impact patients’ clinical outcomes. Lastly, it addresses the challenges of utilizing such technologies and future directions. Providing multiple perspectives on the topic, the book appeals to a wide range of readers, including nurses, clinicians, researchers, technology experts and students, making them familiar with a broad selection of technological interventions and their application in clinical practice. 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Food commodities of African and South Asian countries are especially reported to have aflatoxins well beyond the allowable limits but due to the global trade of food commodities developed countries are also prone towards the perils of aflatoxins. Moreover, climate changes may have a substantial impact on the distribution and global prevalence of aflatoxins in the near future. The International Agency for Research on Cancer (IARC) has classified the aflatoxins as group 1 category carcinogen. Aflatoxins are also reported as teratogenic, mutagenic, growth retardant, immunosuppressant and may also cause nervous system and reproductive system disorders. Preventive approaches involving good manufacturing from “farm to fork” are the major focus of the current food industry. The aim of our book is to provide readers with the most recent data and up-to-date studies from aflatoxins research, with specific focuses on (i) the impact of aflatoxins on human health, (ii) new approaches by the researchers from different parts of the world to degrade aflatoxins and (iii) potential preventive approaches that can significantly lessen the burden of aflatoxins in food products\u003c\/p\u003e","brand":"Gardners","offers":[{"title":"Default Title","offer_id":52915693289751,"sku":null,"price":17479.59,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0679\/6918\/8119\/files\/9783030857622.jpg?v=1781529291"},{"product_id":"all-you-need-to-know-about-spiders-9783030908812","title":"All You Need to Know About Spiders","description":"\u003cp\u003eAll You Need to Know About Spiders Spiders are super predators and devour everything they can overpower. 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In addition, some of the most common spider species in the house and garden are briefly presented with tips for observation.  The authors This book is authored by eight scientists, all of them members of the Association for the Promotion of Spider Research: Wolfgang Nentwig, Jutta Ansorg, Angelo Bolzern, Holger Frick, Anne-Sarah Ganske, Ambros Hänggi, Christin Kropf und Anna Stäubli\u003c\/p\u003e","brand":"Gardners","offers":[{"title":"Default Title","offer_id":52915701088535,"sku":null,"price":6298.05,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0679\/6918\/8119\/files\/9783030908812.jpg?v=1781529329"},{"product_id":"advances-in-experimental-medicine-and-biology-9783030630461","title":"Advances in Experimental Medicine and Biology","description":"\u003cp\u003eRespiratory diseases are leading causes of death and disability globally, with about 65 million people suffering from COPD, and 334 million from asthma, the most common chronic disease. Each year, tens of millions of people develop and can die from from respiratory infections such as pneumonia and TB. Systemic inflammation may induce and exacerbate local inflammatory diseases in the lungs, and local inflammation can in turn cause systemic inflammation. There is increasing evidence of the coexistence of systemic and local inflammation in patients suffering from asthma, COPD, and other lung diseases, and the co-morbidity of two or more local inflammatory diseases often occurs. For example, rheumatoid arthritis frequently occurs together with, and promotes the development of, pulmonary hypertension. This co-morbidity significantly impacts quality of life, and can result in death for those affected.Current treatment options for lung disease are neither effective, nor condition-specific; there is a desperate need for novel therapeutics in the field. Additionally, the molecular and physiological significance of most major lung diseases is not well understood, which further impedes development of new treatments, especially in the case of coexistent lung diseases with other inflammatory diseases. Great progress has been made in recent years in many areas of the field, particularly in understanding the molecular geneses, regulatory mechanisms, signalling pathways, and cellular processes within lung disease, as well as basic and clinical technology, drug discovery, diagnoses, treatment options, and predictive prognoses. This is the first text to aggregate these developments. In two comprehensive volumes, experts from all over the world present state-of-the-art advances in the study of lung inflammation in health and disease. Contributing authors cover well-known as well as emerging topics in basic, translational, and clinicalresearch, with the aim of providing researchers, clinicians, professionals, and students with new perspectives and concepts. The editors hope these books will also help to direct future research in lung disease and other inflammatory diseases, and result in the development of novel therapeutics.\u003c\/p\u003e","brand":"Gardners","offers":[{"title":"Default Title","offer_id":52915734774039,"sku":null,"price":33676.89,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0679\/6918\/8119\/files\/9783030630461.jpg?v=1781529415"}],"url":"https:\/\/payment.letskitaboo.com\/collections\/medical-biography-autobiography.oembed?page=7","provider":"Kitaboo One eStore","version":"1.0","type":"link"}