{"title":"Clinical Medicine (Medical)","description":null,"products":[{"product_id":"medicine-9783031343049","title":"Medicine","description":"\u003cp\u003eThe book presents a multi-disciplinary approach to understanding mechanisms regulating the formation of mineral in vertebrate skeletal and dental tissues. The focus of the book is directed toward the mineralization process, an evolutionarily conserved system in which cells synthesize a complex and unique extracellular matrix into which mineral is deposited. Regulatory control is viewed though lenses that emphasize the genetic, physical-chemical, biochemical, structural, cellular and extracellular aspects of the mineralization process as they relate to crystal nucleation, growth and maturation. Throughout the book, defects in regulation at the genetic and transcriptional levels are linked to the numerous clinical problems associated with the mineralization of bone, cartilage, tendon, tooth, and soft tissues. The book serves as a comprehensive text for basic scientists and scholars working in the many areas that comprise hard tissue research, as well as undergraduate and graduate students, postdoctoral fellows and those contemplating working in the field of biomineralization or who need a review of a specific mineralization topic. The information contained in the book is relevant for clinicians and clinical scientists in the fields of orthopaedic surgery, veterinary medicine, dentistry, endocrinology, aging and genetics.\u003c\/p\u003e","brand":"Gardners","offers":[{"title":"Default Title","offer_id":52894299947287,"sku":null,"price":17454.24,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0679\/6918\/8119\/files\/9783031343049.jpg?v=1781256906"},{"product_id":"current-topics-in-microbiology-and-immunology-9783031180705","title":"Current Topics in Microbiology and Immunology","description":"\u003cp\u003eThe formulation and the technological advancements in RNA biology, chemistry, stability, and encapsulated delivery systems that have enabled the development of fully synthetic mRNA vaccines are discussed in this volume. The applications of the mRNA technology is covered, focusing on infectious diseases but also touching on other indications, such as immunotherapies and molecular therapies. Potent and long-lasting immune responses observed in animal models, encouraging data from early human clinical studies, together with the success of two mRNA-based COVID-19 vaccines support the use of mRNA-based vaccination as an attractive alternative to conventional vaccine approaches. Consequently, the development progress of the technology, particularly on production, capabilities, and clinical development is reviewed. Topics on safety, regulatory issues, and possible challenges to the mRNA vaccination approach round off this book. Thanks to their high potency, the prospect for generic,low-cost manufacturing processes, and entirely synthetic nature, the future for mRNA vaccines is highly promising. Importantly, mRNA vaccines have the potential to minimize the time between pathogen identification and vaccine release with a huge impact on public health. As the mRNA-based vaccination technology has been progressing rapidly, the book is intended to be an end-to-end review series, covering everything from basic RNA biology and preclinical studies to the manufacturing strategy, clinical development and regulatory approval. It provides established RNA researchers and developers with updates on the latest advancements in the field and allows for a quick but comprehensive overview of this transformative technology, its application, and future potential.\u003c\/p\u003e","brand":"Gardners","offers":[{"title":"Default Title","offer_id":52894719050007,"sku":null,"price":17454.24,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0679\/6918\/8119\/files\/9783031180705.jpg?v=1781257908"},{"product_id":"biomedical-and-life-sciences-9783030578145","title":"Biomedical and Life Sciences","description":"\u003cp\u003eThe Science and Business of Drug Discovery is written for those who want to learn about the biopharmaceutical industry and its products whatever their level of technical knowledge. Its aim is to demystify the jargon used in drug development, but in a way that avoids over simplification and the resulting loss of key information. Each of the twenty chapters is illustrated with figures and tables which clarify some of the more technical points being made. Also included is a drug discovery case history which draws the relevant material together into a single chapter. In recognizing that it is difficult to navigate through the many external resources dealing with drug development, the book has been written to guide the reader towards the most appropriate information sources, including those listed in the two appendices.The following topics are covered:Different types of drugs: from small molecules to stem cellsBackground to chemistry of small and large moleculesHistorical background to drug discovery, pharmacology and biotechnologyThe drug discovery pipeline: from target discovery to marketed medicineCommercial aspects of drug discoveryChallenges to the biopharmaceutical industry and its responsesMaterial of specific interest to technology transfer executives, recruiters and pharmaceutical translators\u003c\/p\u003e","brand":"Gardners","offers":[{"title":"Default Title","offer_id":52894816174359,"sku":null,"price":6880.35,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0679\/6918\/8119\/files\/9783030578145.jpg?v=1781258011"},{"product_id":"aaps-introductions-in-the-pharmaceutical-sciences-9783031315053","title":"AAPS Introductions in the Pharmaceutical Sciences","description":"\u003cp\u003eWritten by twenty-five authors from academia, pharmaceutical industry and Pharmacopeias worldwide, this monograph covers the fundamentals and applications of Quality by Design (QbD) and Analytical Quality by Design (AQbD) in a practical and didactic manner. The book starts by describing the motivation and the urgent need for the implementation of the QbD framework in pharmaceutical development, along with the definition of its major elements: Quality Target Product Profile (QTTP), Critical Quality Attributes (CQAs), Critical Process Parameters (CPPs), Critical Material Attributes (CMAs) and the importance of using multivariate methods of Design of Experiments (DOE). The concept of life cycle and regulatory perspectives are discussed. Three chapters are entirely dedicated to DOE theory from screening to optimization designs. Moreover, a comprehensive discussion on modelling and data treatment is presented. Practical aspects of QbD and DOE for pharmaceutical product and process of different dosage forms is included, as well as a practical guide of the input process variables, material attributes, intermediate, and final quality attributes for the most representative pharmaceutical processes. Analytical Quality by Design (AQbD) is also deeply explored, including risk analysis, definitions of Analytical Target Profile (ATP), Method Operable Design Region (MODR) and the life cycle approach, taking into account the compendial and regulatory perspectives. A detailed example of a new chromatographic method for the quality control of a pharmaceutical topical product based on the AQbD procedure is shown. Finally, advanced statistical approaches and DOE methods for extraction studies of bioactive compounds are also presented. The vast amount of information offered in this book provides a comprehensive perspective on QbD, AQbD and DOE principles, essential tools for modern pharmaceutical and analytical development.\u003c\/p\u003e","brand":"Gardners","offers":[{"title":"Default Title","offer_id":52894898192663,"sku":null,"price":16203.04,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0679\/6918\/8119\/files\/9783031315053.jpg?v=1781258318"},{"product_id":"aaps-introductions-in-the-pharmaceutical-sciences-9783031321924","title":"AAPS Introductions in the Pharmaceutical Sciences","description":"\u003cp\u003eCurrently, there are no textbooks on drug product manufacturing technology transfer that incorporate the latest regulatory expectations. Recent guidance from regulatory bodies such as the US FDA, EMEA, WHO, and PIC\/S has adopted the ICH Lifecycle approach harmonizing concepts across regulatory guidance. This allows organizations to align their technology transfer activities for all regulated markets. However, there is a need for consensus and direction in approaching technology transfer, particularly in understanding how to manage the scale-up effects to ensure regulatory compliance.This textbook offers technology transfer solutions and guidance to the pharmaceutical industry. The chapters provide a systematic understanding of applying the technology transfer concepts in pharmaceutical manufacturing, promoting standardization within the industry. Since Stage 1b is not specified in detail within the regulations, pharmaceutical organizations are left to determine the requirementsof the stage. The need to justify the methodologies and utilization of sound science makes it more demanding. The textbook's authors provide innovative solutions for technology transfer challenges, making it a comprehensive reference document. The approaches can be applied to both small-molecule and large-molecule drug product manufacturing segments, addressing the unmet needs of the industry.\u003c\/p\u003e","brand":"Gardners","offers":[{"title":"Default Title","offer_id":52911227502871,"sku":null,"price":11259.55,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0679\/6918\/8119\/files\/9783031321924.jpg?v=1781263744"},{"product_id":"topics-in-medicinal-chemistry-9783030245917","title":"Topics in Medicinal Chemistry","description":"\u003cp\u003eThis book introduces readers to the latest advances in G protein-coupled receptor (GPCR) biology. It reviews our current understanding of the structural basis of ligand binding and allosteric mechanisms, following a decade of technological breakthroughs. Several examples of structure-based drug discovery are presented, together with the future challenges involved in designing better drugs that target GPCRs. In turn, the book illustrates the important concept of GPCR biased signaling in physiological contexts, and presents fluorescent- and light-based methodologies frequently used to measure GPCR signaling or to trace their dynamics in cells upon ligand activation. Taken together, the chapters provide an essential overview and toolkit for new scientific investigators who plan to develop GPCR projects. 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Regulatory agencies have raised the bar for the development and manufacture of antibody-based products, expecting to see the use of Quality by Design (QbD) elements demonstrating an in-depth understanding of product and process based on sound science. Drug delivery systems have become an increasingly important part of the therapy and most biopharmaceuticals for self-administration are being marketed as combination products. A survey of the market indicates that there is a strong need for a new book that will provide \u0026amp;quote;one stop shopping\u0026amp;quote; for the latest information and knowledge of the scientific and engineering advances madeover the last few years in the area of biopharmaceutical product development. The new book entitled Development of Biopharmaceutical Drug Device Products is a reference text for scientists and engineers in the biopharmaceutical industry, academia or regulatory agencies. With insightful chapters from experts in the field, this new book reviews first principles, covers recent technological advancements and provides case studies and regulatory strategies relating to the development and manufacture of antibody-based products.  It covers topics such as the importance of early preformulation studies during drug discovery to influence molecular selection for development, formulation strategies for new modalities, and the analytical techniques used to characterize them.  It also addresses important considerations for later stage development such as the development of robust formulations and processes, including process engineering and modeling of manufacturing unit operations, the design of analytical comparability studies, and characterization of primary containers (pre-filled syringes and vials).Finally, the latter half of the book reviews key considerations to ensure the development and approval of a patient-centered delivery system design. This involves the evolving regulatory framework with perspectives from both the US and EU industry experts, the role of international standards, design control\/risk management, human factors and its importance in the product development and regulatory approval process, as well as review of the risk-based approach to bridging between devices used in clinical trials and the to-be-marketed device.  Finally, case studies are provided throughout.The typical readership would have biology and\/or engineering degrees and would include researchers, scientific leaders, industry specialists and technology developers working in the biopharmaceutical field.\u003c\/p\u003e","brand":"Gardners","offers":[{"title":"Default Title","offer_id":52915516604695,"sku":null,"price":31217.44,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0679\/6918\/8119\/files\/9783030314156.jpg?v=1781526919"},{"product_id":"advances-in-biochemistry-in-health-and-disease-9783031554896","title":"Advances in Biochemistry in Health and Disease","description":"\u003cp\u003eThe concept of \u0026amp;quote;vital amines\u0026amp;quote; as essential nutrients was introduced over a century ago by Dr Casimir Funk. It was suggested that there is a family of organic substances that are required in minute amounts and essential for life. The increase in incorporation of vitamins and supplementation in routine dietary practices is expected to increase. In fact, it has been estimated that 60% of worldwide consumers are taking vitamin supplements on a daily basis, a trend that will most likely rise across the world.This book brings together international experts in the field of vitamins for human health and disease, to update and integrate current understanding on the effects of different lipophilic vitamins on cellular, metabolic and molecular biochemical reactions with respect to different pathophysiological conditions including cardiovascular disease, cancer, metabolic defects, inflammatory and immune diseases. This book is uniquely positioned as it focuses on the biochemistry and molecular biology of lipophilic vitamins in diverse cell systems in relation to human health and disease.The book will certainly stimulate and motivate biomedical researchers and scientists to further explore the relationship between lipophilic vitamins and biological processes, as well as serve as a highly useful resource for nutritional investigators, health professionals, medical students, fellows, residents and graduate students. We hope that the reader will gain knowledge and further understanding of the importance of lipophilic vitamins. The novel insights provided by the contributing authors will assist in advancing preventive medicine worldwide as well as bring forward knowledge that may help in the use of lipophilic vitamins as adjuvant to therapeutic strategies for human disease.\u003c\/p\u003e","brand":"Gardners","offers":[{"title":"Default Title","offer_id":52915601375511,"sku":null,"price":16264.35,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0679\/6918\/8119\/files\/9783031554896.jpg?v=1781527753"},{"product_id":"advances-in-biochemical-engineeringbiotechnology-9783319564609","title":"Advances in Biochemical Engineering\/Biotechnology","description":"\u003cp\u003eThis book review series presents current trends in modern biotechnology. The aim is to cover all aspects of this interdisciplinary technology where knowledge, methods and expertise are required from chemistry, biochemistry, microbiology, genetics, chemical engineering and computer science.Volumes are organized topically and provide a comprehensive discussion of developments in the respective field over the past 3-5 years. The series also discusses new discoveries and applications. Special volumes are dedicated to selected topics which focus on new biotechnological products and new processes for their synthesis and purification. In general, special volumes are edited by well-known guest editors. The series editor and publisher will however always be pleased to receive suggestions and supplementary information. 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Within these cage metal complexes, (metal) ions can be isolated from external factors.The book provides both a classification of the cage compounds and summaries of synthetic approaches. On that basis the authors then describe the unique chemical and physical properties and the resulting reactivity of the cage compounds, as well as practical and potential applications as potent topological drugs and prodrugs, antifibrillogenic agents, radiodiagnostic and radiotherapeutic compounds, paramagnetic probes, single-molecule magnets, electrocatalysts for hydrogen production, (photo)electronic devices, and many more.Readers will find a well-structured and concise overview, with particular emphasis on a review of synthesis and reactivity of various cage metal complexes, summarizing over 400 literature references, clearly presented in over 300 color schemes and figures.\u003c\/p\u003e","brand":"Gardners","offers":[{"title":"Default Title","offer_id":52915806109975,"sku":null,"price":13700.64,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0679\/6918\/8119\/files\/9783319564203.jpg?v=1781530759"},{"product_id":"progress-in-the-chemistry-of-organic-natural-products-9783319455419","title":"Progress in the Chemistry of Organic Natural Products","description":"\u003cp\u003eThe book presents the current state of the art on phytocannnabinoid chemistry and pharmacology and will be of much use to those wishing to understand the current landscape of the exciting and intriguing phytocannabinoid science. The focus is on natural product cannabinoids which have been demonstrated to act at specific receptor targets in the CNS.\u003c\/p\u003e","brand":"Gardners","offers":[{"title":"Default Title","offer_id":52915869679895,"sku":null,"price":34971.04,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0679\/6918\/8119\/files\/9783319455419.jpg?v=1781586169"},{"product_id":"biomedical-and-life-sciences-9783319539133","title":"Biomedical and Life Sciences","description":"\u003cp\u003eThis book describes how microbes can be used as effective and sustainable resources to meet the current challenge of finding suitable and economical solutions for biopharmaceuticals, enzymes, food additives, nutraceuticals, value added biochemicals and microbial fuels, and discusses various aspects of microbial regulatory activity and its applications. It particularly focuses on the design, layout and other relevant issues in industrial microbe applications. Moreover, it discusses the entire microbial-product supply chain, from manufacturing sites to end users, both in domestic and international markets, providing insights into the global marketing of microbes and microbial biomass-derived products. Further, it includes topics concerning the effective production and utilization of eco-friendly biotechnology industries. 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The book retains its interdisciplinary approach and supplies biochemists, cell biologists and biophysicists as well as clinicians in immunology, neurology and cardiology with valuable information on Ca2+ signaling mechanisms, functions, dysfunctions and their consequences.\u003c\/p\u003e","brand":"Gardners","offers":[{"title":"Default Title","offer_id":52916022706455,"sku":null,"price":27463.84,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0679\/6918\/8119\/files\/9783319577326.jpg?v=1781587452"},{"product_id":"biomedical-and-life-sciences-9783319595047","title":"Biomedical and Life Sciences","description":"\u003cp\u003eThe authors show how the pharmaceutical industry faces the development of dermal drugs and provide the only book of its kind that describes how the industry develops and selects dermal drugs, complete with the challenges and opportunities of the field. Delivery of drugs through the skin has been an attractive and challenging area for research, and advances in modern technologies have resulted in a larger number of drugs being delivered transdermally, including conventional hydrophobic small molecule drugs, hydrophilic drugs and macromolecules. Offering the perspective from the industrial side of selection and development of drugs, the primary audience is geared towards the pharmaceutical industry but can also offer valuable information to clinicians, compounding pharmacists, and similarly pharmacy students. 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The chapters contributed deal with methodological peculiarities of syntheses of natural and artificial sugar derived spirocycles as well as their biological applications and other utilities including marketed drugs. Carbohydrates are ubiquitous molecules in nature and participate in a vast number of biological interactions. Especially their conjugates with practically all kinds of primary and secondary metabolic small molecules (and also biomacromolecules) representing valuable tools for glycobiology research and also lead compounds for drug discovery. While monosaccharides per se appear as heterocycles, their natural conjugates frequently exhibit spiro(hetero)cyclic derivatives, in many cases of high therapeutical relevance. As a consequence, the field of carbohydrate-spiro-heterocycles attracts intense interest from both chemical and biomedical aspects therefore this volume will be of interest for synthetic and medicinal chemists and (glyco)biologists, as well as researchers involved in various biomedical fields.\u003c\/p\u003e","brand":"Gardners","offers":[{"title":"Default Title","offer_id":52926048731415,"sku":null,"price":22459.04,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0679\/6918\/8119\/files\/9783030319427.jpg?v=1781594273"},{"product_id":"medicine-9783319471402","title":"Medicine","description":"\u003cp\u003eThis comprehensive volume captures the latest scientific evidence, technological advances, treatments and impact of biotechnology in hyperbaric oxygen therapy. Divided into three distinct sections, the book begins with basic aspects that include history, equipment, safety and diagnostic approaches; this is followed by clinical applications for hyperbaric oxygen therapy in various modalities; the last section provides an overview of hyperbaric medicine as a specialty with best practices from around the world. Integration of multidisciplinary approaches to complex disorders are also covered.Updated and significantly expanded from previous editions, Textbook of Hyperbaric Medicine, 6th Edition will continue to be the definitive guide to this burgeoning field for students, trainees, physicians and specialists.\u003c\/p\u003e","brand":"Gardners","offers":[{"title":"Default Title","offer_id":52927121228055,"sku":null,"price":27463.84,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0679\/6918\/8119\/files\/9783319471402.jpg?v=1781599993"},{"product_id":"aaps-advances-in-the-pharmaceutical-sciences-series-9783319500423","title":"AAPS Advances in the Pharmaceutical Sciences Series","description":"\u003cp\u003eTackling translational medicine with a focus on the drug discovery development-interface, this book integrates approaches and tactics from multiple disciplines, rather than just the pharmaceutical aspect of the field. The authors of each chapter address the paradox between the molecular understanding of diseases, drug discovery, and drug development. Laying out the detailed trends from various fields, different chapters are dedicated to target engagement, toxicological safety assessments, and the compelling relationship of optimizing early clinical studies with design strategies. The book also highlights the importance of balancing the three pillars: sufficient efficacy, acceptable safety and appropriate pharmacokinetics, all of which are crucial to successful efforts in discovery and development. With discussions regarding the combined approaches of molecular research, personalized medicine, pre-clinical and clinical development, as well as targeted therapies-this compendium is a flexible fit, perfect for professionals in the pharmaceutical industry and related academic fields.\u003c\/p\u003e","brand":"Gardners","offers":[{"title":"Default Title","offer_id":52935010025751,"sku":null,"price":31217.44,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0679\/6918\/8119\/files\/9783319500423.jpg?v=1781615879"},{"product_id":"biomedical-and-life-sciences-9783319516202","title":"Biomedical and Life Sciences","description":"\u003cp\u003eThis book studies the production of indole alkaloids in the important medicinal plant Catharanthus roseus (L.) G. Don, commonly known as periwinkle. The anticancer alkaloids, viz. vinblastine and vincristine, are mainly present in the leaves of C. roseus and inhibit the growth of cancer cells by hindering the formation of mitotic apparatus during cell division. Further, vinblastine helps increase the chance of surviving childhood leukemia while vincristine is used to treat Hodgkin's disease. Great efforts have been made to produce these alkaloids at a large scale by the culture of plant cells. In view of this worldwide demand for commercial use, this book explores how to maximize the production of anticancer alkaloids from C. roseus. This reference book will be helpful for research students, teachers, ethnobotanists, pharmacologists and herbal growers who have a strong interest in this anticancer medicinal plant of paramount importance.\u003c\/p\u003e","brand":"Gardners","offers":[{"title":"Default Title","offer_id":52935171899671,"sku":null,"price":16203.04,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0679\/6918\/8119\/files\/9783319516202.jpg?v=1781616783"},{"product_id":"learning-materials-in-biosciences-9783031442568","title":"Learning Materials in Biosciences","description":"\u003cp\u003eThis well-accessible textbook constitutes a practical guide to metabolomics approaches and applications in an integrative manner. Illustrated by numerous real-life examples and case studies the book teaches how to set up and carry out metabolomics experiments, from sample collection to storage techniques, and guides the reader through the potentials and challenges of metabolite analysis. In addition, this textbook shows how to obtain insights into molecular mechanisms deployed in different physiological contexts (e.g., exercise, healthy ageing) as well as in different (metabolic) diseases, be it Diabetes, Cancer, Alzheimer's Disease, Asthma or others. The book brings together knowledge from biochemical, biological, and medical aspects, and further equips the reader with know-how from sample collection and handling to data processing, analysis and interpretation.  This textbook is a must-have for advanced undergraduates and graduate students interested in applied biochemistry and metabolomics, as well as for instructors who teach courses in biomedicine, physiology or biochemistry.\u003c\/p\u003e","brand":"Gardners","offers":[{"title":"Default Title","offer_id":52935856881943,"sku":null,"price":11198.24,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0679\/6918\/8119\/files\/9783031442568.jpg?v=1781618345"},{"product_id":"aaps-advances-in-the-pharmaceutical-sciences-series-9783319548029","title":"AAPS Advances in the Pharmaceutical Sciences Series","description":"\u003cp\u003eThe editors have engaged leading scientists in the field to participate in the development of this book, which is envisioned as a \u0026amp;quote;one of a kind\u0026amp;quote; contribution to the field. 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The book explores this convergence as a multidisciplinary approach that leverages the synergies among digital technologies, material sciences, and biotechnology, aiming to significantly accelerate and broaden the scope of scientific breakthroughs.This volume provides a scholarly account of the emerging opportunities catalyzed by bioconvergence, emphasizing the necessity for rigorous ethical frameworks and standards as biotechnologies and digital tools converge to explore new frontiers. It delves into the challenges of financing scientific advancement and articulates how funding underpins multidisciplinary research efforts. Featuring Israel as a leader in this revolutionary field, the book meticulously outlines the Israeli ecosystem as a paradigm of innovation in bioconvergence. 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It also addresses acquired thrombophilia, highlighting the significant impact of factors such as hyperhomocysteinemia and the influence of medications, lifestyle choices, and underlying health conditions on thrombosis risk. Each chapter clarifies the principles behind various laboratory assays, detailing the preanalytical variables that can affect results and guiding the interpretation of findings. Real-world challenges in thrombophilia testing such as during pregnancy, the use of oral contraceptives, and monitoring anticoagulation therapy are specifically examined. Written in a clear yet comprehensive style, this book is aimed at thrombosis specialists, hematologists, laboratory scientists, and students. 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It also shows promise in treating cardiovascular and neurodegenerative diseases and diabetes, offering hope for those affected.The cancer-protecting properties of Brassica plants are mediated through compounds that induce a variety of physiological processes, including antioxidant action, detoxifying enzymes, inducing apoptosis, and cell cycle regulation. Glucosinolate breakdown products can affect several stages of cancer development, including the inhibition of activation enzymes (phase I) and the induction of detoxification enzymes (phase II). Isothiocyanates and indole products formed from glucosinolates regulate cancer cell development by regulating target enzymes, controlling apoptosis, inhibiting angiogenesis, metastasis, and the migration of cancer cells, and blocking the cell cycle.Sulforaphane, found in abundance in broccoli sprouts, plays a crucial role in upregulating the transcriptional activity of specific genes and restoring epigenetic alterations. 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The warm temperature triggers the Maillard reaction, giving it a dark brown color and producing health-promoting compounds not found in raw garlic. In 1858, Louis Pasteur described the antibacterial effect of garlic, highlighting its broad antibiotic spectrum against both gram-positive and gram-negative bacteria. Notably, raw garlic juice is effective against many common pathogenic intestinal bacteria that cause diarrhea; garlic also works against strains resistant to antibiotics. The combination of garlic with antibiotics shows partial or full synergism, and a complete absence of resistance has been observed repeatedly. Additionally, garlic inhibits toxin production by microorganisms.  In 1990, the US National Cancer Institute launched the Designer Food Program to identify foods that play important roles in cancer prevention. The program concluded that garlic might be the most powerful cancer-preventive food. 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