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This edition addresses the practical considerations for, and scope of hospital 3D printing facilities, image segmentation and post-processing for Computer Aided Design (CAD) and 3D printing. The book provides details regarding technologies and materials for medical applications of 3D printing, as well as practical tips of value for physicians, engineers, and technologists. Individual, comprehensive chapters span all major organ systems that are 3D printed, including cardiovascular, musculoskeletal, craniomaxillofacial, spinal, neurological, thoracic, and abdominal. The fabrication of maxillofacial prosthetics, the planning of head and neck reconstructions, and 3D printed medical devices used in cranial reconstruction are also addressed. The second edition also includes guidelines and regulatory considerations, costs and reimbursement for medical 3D printing, quality assurance, and additional applications of CAD such as virtual reality. 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The chapters focus on the genetics, genomics, epigenetics and physiology of stem cells models, together with technological advances on molecular biology such as CRISPR\/Cas9 or epigenetic editing, that will be instrumental in the future of human disease modeling and treatment. In base of the limitations of current disease models and in front of the unmet necessity of finding therapeutical interventions for human disorders, the availability of stem cell technology has opened new doors for several fields. The unlimited self-renewal capacity and more extensive differentiation potential of stem cells offers a theoretically inexhaustible and replenishable source of any cell subtype. 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Consequent socio-economic burden is tremendous. Unprecedented decrease in age of maladaptive individuals has been reported. The absolute majority of expanding non-communicable disorders carry a chronic character, over a couple of years progressing from reversible suboptimal health conditions to irreversible severe pathologies and cascading collateral complications. The paradigm change from reactive to predictive preventive and personalisedmedicine is essential to promote population health by application of individualised patient profiling, multi-parametric analysis leading to cost-effective targeted prevention. To this end, inadequate data for risk assessment on speed and urgency of COVID-19, combined with increased globalization of human society, led to the rapid spread of COVID-19. 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In addition, this new edition offers a wider international perspective: new chapters are included covering Advanced Therapy Medicinal Products regulations in India, Malaysia, Spain and Thailand, the European Pharmacopoeia texts for gene therapy medicinal products as well as international harmonization programs. Each chapter, authored by experts from various regulatory bodies throughout the international community, walks the reader through the applications of nonclinical research to translational clinical research to licensure and therapeutic use of these innovative products.  More specifically, each chapter offers insights into fundamental considerations that are essential for developers of Advanced Therapy Medicinal Products in the areas of product quality, pharmacology and toxicology, clinical trial design and HTA pathways, as well as pertinent 'must-know' guidelines and regulations. Regulatory Aspects of Gene Therapy and Cell Therapy Products: a Global Perspective is part of the American Society of Gene \u0026amp; Cell Therapy sub-series of the highly successful Advances in Experimental Medicine and Biology series. 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New technologies and advancements have the potential to extend the reach of health professionals while improving quality and efficiency of service delivery and reducing costs within the public and the private health systems. The chapters highlight the barriers faced by the global healthcare workforce in using technology to promote health and human rights of communities:Role of Digital Health, mHealth, and Low-Cost Technologies in Advancing Universal Health Coverage in Emerging EconomiesTelehealth and Homecare AgenciesTechnology and the Practice of Health Education in Conflict ZonesThe Worldwide Digital Divide and Access to Healthcare TechnologyTechnology for Creating Better Professional Teams to Strengthen Healthcare SystemsGlobal Public Health Disaster Management and TechnologyAs a resource on the evolution of technology as a valuable and integral component in the promotion and practice of public health and health care, with a focus on SDG 3 targets, Technology and Global Public Health should engage students, instructors, practitioners, and other professionals interested in public health, universal health care, health technology, digital health, and health equity.Dr. Murthy has been a respected leader and mentor on scientific health-related matters within the UN system for many years. Her book develops a theoretical system connecting concepts that have coined global public health with the rapid development of technology, all with the focus to achieve Sustainable Development Goal number three, within the time frame set by World Leaders.          -  Henry L. Mac-Donald, Former Permanent Representative of Suriname to the United Nations\u003c\/p\u003e","brand":"Gardners","offers":[{"title":"Default Title","offer_id":52894377378071,"sku":null,"price":7422.41,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0679\/6918\/8119\/files\/9783030463557.jpg?v=1781257357"},{"product_id":"lecture-notes-in-computer-science-9783030009281","title":"Lecture Notes in Computer Science","description":"\u003cp\u003eThe four-volume set LNCS 11070, 11071, 11072, and 11073 constitutes the refereed proceedings of the 21st International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2018, held in Granada, Spain, in September 2018.The 373 revised full papers presented were carefully reviewed and selected from 1068 submissions in a double-blind review process. The papers have been organized in the following topical sections: Part I: Image Quality and Artefacts; Image Reconstruction Methods; Machine Learning in Medical Imaging; Statistical Analysis for Medical Imaging; Image Registration Methods. Part II: Optical and Histology Applications: Optical Imaging Applications; Histology Applications; Microscopy Applications; Optical Coherence Tomography and Other Optical Imaging Applications. Cardiac, Chest and Abdominal Applications: Cardiac Imaging Applications: Colorectal, Kidney and Liver Imaging Applications; Lung Imaging Applications; Breast Imaging Applications; Other Abdominal Applications. Part III: Diffusion Tensor Imaging and Functional MRI: Diffusion Tensor Imaging; Diffusion Weighted Imaging; Functional MRI; Human Connectome. Neuroimaging and Brain Segmentation Methods: Neuroimaging; Brain Segmentation Methods.Part IV: Computer Assisted Intervention: Image Guided Interventions and Surgery; Surgical Planning, Simulation and Work Flow Analysis; Visualization and Augmented Reality. Image Segmentation Methods: General Image Segmentation Methods, Measures and Applications; Multi-Organ Segmentation; Abdominal Segmentation Methods; Cardiac Segmentation Methods; Chest, Lung and Spine Segmentation; Other Segmentation Applications.\u003c\/p\u003e","brand":"Gardners","offers":[{"title":"Default Title","offer_id":52894377672983,"sku":null,"price":12080.49,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0679\/6918\/8119\/files\/9783030009281.jpg?v=1781257365"},{"product_id":"stem-cells-in-urology-9783030414764","title":"Stem Cells in Urology","description":"\u003cp\u003eThis contributed volume emphasizes the potential of stem cells to be pertained in the urology field and attempts to disclose the history of the field up to the latest advances to date. It gathers the majority of papers that advocate utilizing stem cells as the best option for treating, diagnosing, and managing diseases related to urological system. This book covers a broad spectrum of issues, including mesenchymal stem cells, cancer stem cells, organoids, regenerative medicine, erectile dysfunction, bladder dysfunction, and kidney transplant. From several decades ago, as characteristic features of stem cells have been explored, it has attracted a great amount of interests. In view of their multiple capacity of differentiating into various lineages, many studies were conducted to assess their beneficial potential. Despite considerable progress into applying stem cells in animal models, for translating into clinical practices there are several obstacles to be resolved. However, few clinical studies have been performed in each field and outcomes were delightful. There is an ongoing hope for stem cells to someday, be the mainstream treatments of urological diseases, although stem cells treatments already exist they are not well-known. Indeed, this book is essential for anyone who is working with the purpose of employing stem cells to treat the urological diseases and discusses at length the latest advances as well as their limitations.\u003c\/p\u003e","brand":"Gardners","offers":[{"title":"Default Title","offer_id":52894377967895,"sku":null,"price":12080.49,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0679\/6918\/8119\/files\/9783030414764.jpg?v=1781257367"},{"product_id":"subcellular-biochemistry-9783319496740","title":"Subcellular Biochemistry","description":"\u003cp\u003eThis book provides the readers with an up-to-date review of the design, structure and function of a representative selection of fibrous proteins in both health and disease. The importance of the a-helical coiled coil, a conformational motif based on the heptad repeat in the amino acid sequence of all a-fibrous proteins (and parts of some globular proteins) is underlined by three Chapters devoted to its design, structure, function and topology.  Specific proteins covered in the text and which depend on the coiled coil for their structure and function, include the intermediate filament proteins, tropomyosin, myosin, paramyosin, fibrin and members of the spectrin superfamily. Also described are fibrous proteins based on the -pleated sheet and collagen conformations. Recombinant structural proteins, especially of silk and collagen, are discussed in the context of developing new biomaterials with varied applications. Established researchers and postgraduate students in the fields of protein chemistry, biochemistry and structural biophysics will find Fibrous Proteins: Structures and Mechanisms to be an invaluable collection of topical reviews that describe the basic advances made in the field of fibrous proteins over the past decade. This book, written by recognized authorities in the field, provides a clear account of the current status of fibrous protein research and, in addition, establishes the basis for deciding the most appropriate directions for future activity, including the applications of protein engineering and the commercial exploitation of new biomaterials.\u003c\/p\u003e","brand":"Gardners","offers":[{"title":"Default Title","offer_id":52894378590487,"sku":null,"price":26928.02,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0679\/6918\/8119\/files\/9783319496740.jpg?v=1781257383"},{"product_id":"advances-in-experimental-medicine-and-biology-9783031038730","title":"Advances in Experimental Medicine and Biology","description":"\u003cp\u003eThis book covers the latest developments in tissue electrical conductivity and current density imaging, increasingly popular as well as challenging applications of MRI. These applications are enabled by the acquisition of high-quality MR phase images. This book provides a practical description of the MRI physics needed to understand and acquire phase images in MRI and the key details required to reconstruct them into conductivity, current density or electric field distributions. Comprehensive details are provided about the electrical properties of biological tissues, computational modeling considerations, experimental methods, construction of non-biological and biological phantoms and MRI pulse sequences. An inclusive review of image reconstruction algorithms, and their potential applications is provided for applications directed at determining current density or electric fields, such as in transcranial DC or AC stimulation techniques; as well as electrical conductivity reconstructions that may be of use in quantitative MRI applications used to detect cancer or other pathologies. This is an excellent book for undergraduate and graduate students beginning to explore phase, current density, and conductivity imaging in MRI, and will also be of great use to researchers interested in the area of MR-based electrical property imaging.\u003c\/p\u003e","brand":"Gardners","offers":[{"title":"Default Title","offer_id":52894378688791,"sku":null,"price":24228.47,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0679\/6918\/8119\/files\/9783031038730.jpg?v=1781257388"},{"product_id":"parasitic-protozoa-of-farm-animals-and-pets-9783319701325","title":"Parasitic Protozoa of Farm Animals and Pets","description":"\u003cp\u003eThis book provides an in-depth yet concise overview of the most common and emerging protozoa that cause diseases in both farm animals and companion animals. As outlined in the concise introduction, pathogenic protozoans represent an evolutionary highly diverse and little understood group of disease-causing microorganisms. For each of the featured parasitic unicellular eukaryotes, it discusses the morphology, lifecycle, epidemiology and host-pathogen interactions. In addition, the book highlights the latest developments in diagnostic methods, as well as prevention and treatment strategies. Thorough information on genomes and genetic manipulation strategies for some of the protozoa covered in this book is also included. Infections involving parasitic protozoa can cause productivity losses and\/or reduce the quality of life of infected animals. Some infections are zoonotic, posing an on-going public health threat. In most cases, prevention and treatment are either non-existent or need considerable improvement. On the other hand, a great deal of research has recently been conducted on these organisms, yielding valuable new information on their global distribution and revealing the mechanisms of host-pathogen interactions at the molecular level - and essential insights that can be used for the development of new control tools. This book includes extensive information on both basic aspects and recent scientific discoveries on these protozoa and thus constitutes a unique resource for students, veterinarians, and researchers alike.\u003c\/p\u003e","brand":"Gardners","offers":[{"title":"Default Title","offer_id":52894380491031,"sku":null,"price":14780.04,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0679\/6918\/8119\/files\/9783319701325.jpg?v=1781257438"},{"product_id":"lecture-notes-in-computer-science-9783319675619","title":"Lecture Notes in Computer Science","description":"\u003cp\u003eThis book constitutes the refereed joint proceedings of the International Workshop on Fetal and Infant Image Analysis, FIFI 2017, and the 6th International Workshop on Ophthalmic Medical Image Analysis, OMIA 2017, held in conjunction with the 20th International Conference on Medical Imaging and Computer-Assisted Intervention, MICCAI 2017, in Quebec City, QC, Canada, in September 2017. The 8 full papers presented at FIFI 2017 and the 20 full papers presented at OMIA 2017 were carefully reviewed and selected. The FIFI papers feature research on advanced image analysis approaches focused on the analysis of growth and development in the fetal, infant and paediatric period. The OMIA papers cover various topics in the field of ophthalmic image analysis.\u003c\/p\u003e","brand":"Gardners","offers":[{"title":"Default Title","offer_id":52894380818711,"sku":null,"price":6072.63,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0679\/6918\/8119\/files\/9783319675619.jpg?v=1781257447"},{"product_id":"springer-series-in-translational-stroke-research-9783319666792","title":"Springer Series in Translational Stroke Research","description":"\u003cp\u003eThis book discusses recent advances in the field of translational stroke research. The editors have designed the book to provide new insight into the importance of regeneration and repair mechanisms for stroke victims. The editors have brought together a talented group of international stroke researchers and clinicians to contribute to this volume, which is written for students, researchers and physicians in biotechnology, neurosciences, neurology, neuroradiology and neurosurgery.Throughout the world, stroke is still a leading cause of mortality and morbidity; there are 152,000 strokes in the United Kingdom, 62,000 in Canada, and approximately 15 million people worldwide. Large communities of stroke survivors are eagerly awaiting scientific advances in translational stroke research related to regeneration and recovery of function that would offer new therapeutics for rehabilitation and regeneration utilizing novel stem cell and molecular-based approaches. This volume will allow the reader to undersnd the future of stroke treatment from its inception in the laboratory through to clinical trial design. The reader will learn about the recent advances made in these areas related to basic and applied stroke research and their translational potential.Dr. Paul A. Lapchak is Professor of Neurology and Director of Translational Research in the Departments of Neurology \u0026amp; Neurosurgery at Cedars-Sinai Medical Center in Los Angeles CA, USA. Dr. Lapchak is an internationally recognized expert conducting translational drug development research for ischemic and hemorrhagic stroke. Dr. John H. Zhang is Professor of Anesthesiology, Neurosurgery, Neurology, and Physiology, and Director, Center for Neuroscience Research at Loma Linda University School of Medicine, Loma Linda, CA, USA. Dr. Zhang is an internationally recognized expert working on drug development for hemorrhagic stroke.\u003c\/p\u003e","brand":"Gardners","offers":[{"title":"Default Title","offer_id":52894384161047,"sku":null,"price":17479.59,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0679\/6918\/8119\/files\/9783319666792.jpg?v=1781257536"},{"product_id":"plastic-and-aesthetic-regenerative-surgery-and-fat-grafting-9783030774554","title":"Plastic and Aesthetic Regenerative Surgery and Fat Grafting","description":"\u003cp\u003eReaders will discover the relatively new and rapidly growing field of regenerative surgery and fat grafting, valuable for numerous plastic surgery, reconstructive, and aesthetic\/cosmetic essentials.Though many books have covered specific areas or topics in regenerative surgery, the market lacks a work that tackles the full spectrum of regenerative surgery and its clinical application. This book responds to that need and presents chapters written by the best: world-renowned surgeons in their field.After an introduction that reflects basic research, most of the book focuses on clinical experience as it relates to applied techniques of processing fat and on the different uses from head to toe. Readers will learn about the history of regenerative surgery, important definitions and background information, and the evidence supporting the use of regenerative surgery. Practitioners will also find valuable guidance regarding the application of stem cells, evaluation of patient needs, and operative techniques for fat transfer. Subsequent chapters address topics such as graft types, the skin, wound healing, scar treatment, osteoarthritis, burns, scleroderma, hair rejuvenation, facial enhancement combined with facelift, chin augmentation with fat, and breast argumentation or reconstruction with fat. Particular attention is paid to gluteal augmentation with fat, body contouring, genital male and female rejuvenation, and upper and lower extremity regenerative surgery. Surgical anatomy and complications treatment and prevention were emphasized when applied. This resulted is two volumes that encompass 114 chapters, with multiple figures, and video clips, written by 242 authors (including 72 female colleagues) from five continents.Highly informative and carefully structured, this book provides invaluable insight for beginners and experienced plastic surgeons alike, while benefitting advanced surgeons, specialists, and undergraduate and graduate students.\u003c\/p\u003e","brand":"Gardners","offers":[{"title":"Default Title","offer_id":52894387699991,"sku":null,"price":26928.02,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0679\/6918\/8119\/files\/9783030774554.jpg?v=1781257545"},{"product_id":"nutrition-and-health-9783319461892","title":"Nutrition and Health","description":"\u003cp\u003eThis fully revised and updated new edition provides a comprehensive look at nitrite and nitrate and their effect on human health and disease. The first section describes the biochemical analysis of nitrite and nitrate and its role in human physiology. The book then shifts to sources of human exposure of nitrite and nitrate, including environmental and dietary. Finally, the last section discusses nitric oxide-based therapeutics and how nitrite and nitrate biochemistry can be safely harnessed to improve human health. Each chapter provides a balanced, evidence-based view and heavily cites the most recent published literature. They follow a strict chapter format which includes keywords, key points, a conclusion highlighting major findings, and extensive references.The second edition contains new chapters on nitrite and nitrate in age medicine, nitrite and nitrate as a treatment for hypertension, and nitrite and nitrate in exercise performance. Additionally, the editors have expanded the biochemistry section to include chapters on nitrate reducing oral bacteria, nitrite mediated S-Nitrosation, epigenetics and the regulation of nitric oxide, and nitrite control of mitochondrial function.Nitrate and Nitrite in Human Health and Disease, 2e, will be of interest to health professionals, nutritionists, dieticians, biomedical scientists, and food scientists.\u003c\/p\u003e","brand":"Gardners","offers":[{"title":"Default Title","offer_id":52894404116759,"sku":null,"price":10730.72,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0679\/6918\/8119\/files\/9783319461892.jpg?v=1781257565"},{"product_id":"biomedical-and-life-sciences-9783031295447","title":"Biomedical and Life Sciences","description":"\u003cp\u003eRecent discoveries in microbiology are hard to grasp for those unfamiliar with scientific jargon, and the research data can be overwhelming even for those working in other scientific fields. This book aims to remedy this situation by presenting the most interesting findings and current trends in microbiology in an easy-to-read and understandable format.The first part tells the story of the beginnings of microbiology itself and introduces the reader to the founders of this fascinating research discipline. The second part focuses on communication between microorganisms and how they organize themselves into fascinating microbial cities called biofilms . The reader also learns how bacteria exchange genetic material - mechanisms that are the root of the emergence of multidrug-resistant superbugs, pathogens that pose a major burden to human health and our healthcare systems. The third part is devoted to the latest techniques being used by scientists to study, control, and manipulate microorganisms for our benefit. The final part links the first three parts together and highlights how infectious diseases, including coronaviruses, can be transmitted from animals to humans, how global warming is affecting emerging diseases, and provides information on the actions that need to be taken to get ahead of pathogenic microbes and future pandemics. This comprehensive, state-of-the-art book is intended for anyone interested in microbiology and epidemiology, from biology and biomedical students in schools and colleges, to patients suffering from infectious diseases who want to learn more about their condition.The concepts covered in this book contribute to UN Sustainable Development Goal 3: Health and Well-Being.\u003c\/p\u003e","brand":"Gardners","offers":[{"title":"Default Title","offer_id":52894433509655,"sku":null,"price":5397.75,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0679\/6918\/8119\/files\/9783031295447.jpg?v=1781257600"},{"product_id":"biology-of-extracellular-matrix-9783030997083","title":"Biology of Extracellular Matrix","description":"\u003cp\u003eThis book introduces the most important and best studied extracellular and pericellular molecules of the tumor microenvironment. It gives a comprehensive overview of their role in tumor development and cancer progression.Twelve chapters deal with the biochemical and biophysical background of extracellular matrix (ECM) changes in the tumor stroma compared to the physiological state. The reader learns about the major ECM components that are deregulated during cancer development and how they are associated with cancer progression associated with survival, inflammation process, among others. These are followed by recent data about the cooperative activity of extracellular matrix in tumor metabolism, promoting cancer progression.Two chapters focus specifically on the critical role of the ECM in tumor angiogenesis, linking this process to cellular infiltration and metastatic behavior of tumors. The final part describes how the ECM influences the success of immuno- and chemotherapy in cancer patients, its potential as biomarkers for diagnosis, prognosis, and therapeutic target, as well as the mechanism of resistance-associated changes in the ECM.   This book is an interesting read for anyone who want to know more about ECM and cancer biology. Early career scientists can use it as an introduction to the field, offering an excellent tool for studying ECM. Advanced researchers and clinicians can gain a broader overview of the subject, considering the role of ECM for influencing every cancer hallmark as well as in the response of cancer treatments. The work serves to inspire future research and shows that the ECM should be considered as an important factor in the development of cancer therapeutics.   The series \u0026amp;quote;Biology of Extracellular Matrix\u0026amp;quote; is published in collaboration with the American Society for Matrix Biology and the International Society for Matrix Biology.\u003c\/p\u003e","brand":"Gardners","offers":[{"title":"Default Title","offer_id":52894453006615,"sku":null,"price":21528.92,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0679\/6918\/8119\/files\/9783030997083.jpg?v=1781257611"},{"product_id":"nanotechnology-in-the-life-sciences-9783031102202","title":"Nanotechnology in the Life Sciences","description":"\u003cp\u003eAntibiotics, the backbone of modern clinical-medicine, are facing serious challenges from emerging antimicrobial-resistance (AMR), a complicated phenomenon expanding in bacterial species, from nosocomial to community origins, where microbes are no longer sensitive to a range of commonly used antibiotics. AMR has exploded in recent years and is posing a serious threat to human health and survival. This necessitates novel and effective ways of diagnosis, drug-delivery, and treatment; nanotechnology and advanced nanomaterials are hailed as a potent solution in containing AMR.The main thrust of this volume is to explain the most current research on the central theme of potential use of nano-approaches for diagnosis, detection, drug-delivery and as antimicrobial agents against drug-resistant pathogenic microbes. This book provides an integrated blend of basic and advanced information for students, scholars, scientists and practitioners, interested or already engaged in research in these areas. We have brought together leading international authors to present and highlight various aspects of nanotechnology in combating AMR in WHO-prioritized microbes. Topics range from advances in nanomaterial synthesis, characterization, functionalization and improvisation, as well as applications in sensing, diagnosis of AMR, and their therapeutic and drug-delivery potential against MDR and XDR microbial phenotypes.\u003c\/p\u003e","brand":"Gardners","offers":[{"title":"Default Title","offer_id":52894456316183,"sku":null,"price":20179.14,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0679\/6918\/8119\/files\/9783031102202.jpg?v=1781257617"},{"product_id":"advances-in-experimental-medicine-and-biology-9783031084911","title":"Advances in Experimental Medicine and Biology","description":"\u003cp\u003eThis book covers the wide set of well-regulated virulence factors and defense mechanisms of Pseudomonas aeruginosa focusing on stress responses and the evolution of this opportunistic human pathogen.Pseudomonas aeruginosa is responsible for one out of ten hospital infections.  Additionally, this Gram-negative bacterium is accountable for persistent infections in immunocompromised individuals and the leading cause of chronic lung infections in cystic fibrosis patients. This book provides insight on the metabolic versatility of Pseudomonas aeruginosa and its mechanisms for biofilm formation that make this organism highly efficient  in causing infections.  The book invites the readers to learn more about the intrinsic ability of Pseudomonas aeruginosa to resist a wide variety of antimicrobial agents due to the concerted action of multidrug efflux pumps, antibiotic-degrading enzymes, and the low permeability of bacterial cellular envelopes. Particular focus is put on the evolutionary role of different types of protein-secretion systems in pathogenesis, flagella and their role in chemotaxis and surface sensing, and host-pathogen interactions.This book is a useful introduction to the field for junior scientists interested in the biology and pathogenesis of Pseudomonas aeruginosa. It is also an interesting read for advanced scientists and medical specialists working within this field, providing a broader view of the topic beyond their specific area of specialization.\u003c\/p\u003e","brand":"Gardners","offers":[{"title":"Default Title","offer_id":52894687330583,"sku":null,"price":17479.59,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0679\/6918\/8119\/files\/9783031084911.jpg?v=1781257866"},{"product_id":"molecular-basis-of-resilience-9783319981642","title":"Molecular Basis of Resilience","description":"\u003cp\u003eThis book illuminates mechanisms of resilience.  Threats and defense systems lead to adaptive changes in gene expression. Environmental conditions may dampen adaptive responses at the level of RNA expression. The first seven chapters elaborate threats to human health. Human populations spontaneously invade niche boundaries exposing us to threats that drive the resilience process. Emerging RNA viruses are a significant threat to human health. Antiviral drugs are reviewed and how viral genomes respond to the environment driving genome sequence plasticity.  Limitations in predicting the human outcome are described in \u0026amp;quote;nonlinear anomalies.\u0026amp;quote; An example includes medical countermeasures for Ebola and Marburg viruses under the \u0026amp;quote;Animal Rule.\u0026amp;quote; Bacterial infections and a review of antibacterial drugs and bacterial resilience mediated by horizontal gene transfer follow. Chapter 6 shifts focus to cancer and discovery of novel therapeutics for leukemia. The spontaneous resolution of AML in children with Down syndrome highlights human resilience. Chapter 7 explores chemicals in the environment.  Examples of chemical carcinogenesis illustrate how chemicals disrupt genomes. Historic research ignored RNA damage from chemically induced nucleic acid damage.  The emergence of important forms of RNA and their possible role in resilience is proposed.Chapters 8-10 discuss threat recognition and defense systems responding to improve resilience.  Chapter 8 describes the immune response as a threat recognition system and response via diverse RNA expression.  Oligonucleotides designed to suppress specific RNA to manipulate the immune response including exon-skipping strategies are described.   Threat recognition and response by the cytochrome P450 enzymes parallels immune responses.  The author proposes metabolic clearance of small molecules is a companion to the immune system. Chapter 10 highlights RNA diversity expressed from a single gene. Molecular Resilience  lists paths to RNA transcriptome plasticity forms the molecular basis for resilience.Chapter 11 is an account of ExonDys 51, an approved drug for the treatment of Duchenne muscular dystrophy.   Chapter 12 addresses the question what informs molecular mechanisms of resilience? that drives the limits to adaptation and boundaries for molecular resilience. He speculates that radical oxygen, epigenetic modifications, and ligands to nuclear hormone receptors play critical roles in regulating molecular resilience.\u003c\/p\u003e","brand":"Gardners","offers":[{"title":"Default Title","offer_id":52894694048023,"sku":null,"price":17479.59,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0679\/6918\/8119\/files\/9783319981642.jpg?v=1781257876"},{"product_id":"medicine-9783319968094","title":"Medicine","description":"\u003cp\u003eThis book provides a quick reference guide for clinicians in radiation oncology. It is designed to be an intuitive and easily reviewed study guide for board or maintenance of certification examinations, as well as a quick reference for residents and established radiation oncologists who need a refresher.The text begins with a general pearls chapter that radiation oncologists should consider in all aspects of their practice, including cancer visibility, dosing, counseling recommendations, and toxicity management. The subsequent chapters then delve into different cancer disease sites, including pediatrics, central nervous system, head and neck, thoracic, breast, gastrointestinal, gynecologic, genitourinary, hematologic, soft tissue, palliative, and radiophysics\/radiobiology. Within each chapter, each disease and its recommended approach is then summarized in only a few pages, allowing a focus on the most essential information. Bullet points, figures, tables, and images make for an intuitive reader experience. Recommendations are taken from the American Society for Radiation Oncology (ASTRO), the European Society for Radiation Oncology (ESTRO), and the National Comprehensive Cancer Network (NCCN).  Planning guides for imaging, diagnosis, and staging offer readers a starting point in approaching each patient based on disease origin, and dosing guidelines then detail consideration for treatment methods. Each chapter additionally includes disease-specific pearls and key points to test the knowledge reviewed in the chapters. Experts in the disease sites from the United States serve as senior authors on each chapter.  The authors include all diseases associated with radiation oncology training to ensure a comprehensive resource for exam studying and clinical care. Residents, trainees, and established radiation oncologists find this an ideal study resource for both board and certification exams, as well as an easily accessible aidduring practice.\u003c\/p\u003e","brand":"Gardners","offers":[{"title":"Default Title","offer_id":52894700732695,"sku":null,"price":10730.72,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0679\/6918\/8119\/files\/9783319968094.jpg?v=1781257885"},{"product_id":"advanced-practice-in-nursing-9783319971032","title":"Advanced Practice in Nursing","description":"\u003cp\u003eDeveloped under the direction of the International Council of Nurses (ICN), this book is part of a series exploring advanced practice globally. It is the first known volume to provide an international view of the advanced practice role of clinical nurse specialist (CNS). It features an in-depth examination of advanced speciality practice in nursing, and the advanced practice role of the clinical CNS. Content includes models of practice, core practice competencies, curricular recommendations, practice outcomes, and regulatory requirements related to scope of practice. The CNS role and practice as implemented in North America, Europe, Asia and Oceania are examined in the context of the country's healthcare system, educational traditions and regulatory requirements. Exemplars describe role implementation in various specialty practices and discuss how the role is implemented to advance nursing and improve clinical and fiscal outcomes. Measurement and evaluation ofCNS practice in the context of countries and health care systems are examined. For practicing CNSs, this book provides an in-depth examination of the role from the global perspective; for administrators it provides a foundational understanding of the CNS role and practice and performance expectations. Educators will use the book as a resource for curriculum development, whereas students will offers an expanded global view of the role. Advanced practice roles, including the CNS, are continuing to evolve. This book makes important contributions to a global understanding of the CNS role.\u003c\/p\u003e","brand":"Gardners","offers":[{"title":"Default Title","offer_id":52894707286295,"sku":null,"price":6072.63,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0679\/6918\/8119\/files\/9783319971032.jpg?v=1781257894"},{"product_id":"medicine-9783319969060","title":"Medicine","description":"\u003cp\u003eThis unique collection synthesizes insights and evidence from innovators in consumer informatics and highlights the technical, behavioral, social, and policy issues driving digital health today and in the foreseeable future. Consumer Informatics and Digital Health presents the fundamentals of mobile health, reviews the evidence for consumer technology as a driver of health behavior change, and examines user experience and real-world technology design challenges and successes. Additionally, it identifies key considerations for successfully engaging consumers in their own care, considers the ethics of using personal health information in research, and outlines implications for health system redesign. The editors' integrative systems approach heralds a future of technological advances tempered by best practices drawn from today's critical policy goals of patient engagement, community health promotion, and health equity. Here's the inside view of consumer health informatics and key digital fields that students and professionals will find inspiring, informative, and thought-provoking. Included among the topics:* Healthcare social media for consumer informatics* Understanding usability, accessibility, and human-centered design principles* Understanding the fundamentals of design for motivation and behavior change* Digital tools for parents: innovations in pediatric urgent care* Behavioral medicine and informatics in the cancer community* Content strategy: writing for health consumers on the web* Open science and the future of data analytics* Digital approaches to engage consumers in value-based purchasingConsumer Informatics and Digital Health takes an expansive view of the fields influencing consumer informatics and offers practical case-based guidance for a broad range of audiences, including students, educators, researchers, journalists, and policymakers interested in biomedical informatics, mobile health, information science, and population health. It has as much to offer readers in clinical fields such as medicine, nursing, and psychology as it does to those engaged in digital pursuits.\u003c\/p\u003e","brand":"Gardners","offers":[{"title":"Default Title","offer_id":52894710661399,"sku":null,"price":12080.49,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0679\/6918\/8119\/files\/9783319969060.jpg?v=1781257900"},{"product_id":"microbial-communities-in-aquaculture-ecosystems-9783030161903","title":"Microbial Communities in Aquaculture Ecosystems","description":"\u003cp\u003eThis book sheds light on the major functions of microbial communities in aquaculture ecosystems, showing that by recycling nutrients, degrading organic matter and preventing disease outbreaks, a variety of microbes are truly beneficial to a wide range of aquaculture industries. It discusses how deteriorating environmental quality enables some microbial strains to trigger disease, describes the development of highly sustainable tools to improve water quality, and identifies crucial factors that endanger microbial homeostasis in aquaculture ecosystems.The book also covers post-antibiotic approaches for preventing and treating opportunistic microbial infections based on harnessing environmental and fish-associated microbial communities. Furthermore, it explores how manipulating and engineering these complex microbial communities using bio-agents such as probiotics, phages, natural nutritional additives, or with fine-tuned biofilters will open the door for new ways to develop a more sustainable and cost-effective aquaculture industry. Including an accessible presentation of modern high-throughput sequencing technology to identify host-microbial interactions in aquaculture ecosystems, this book is a valuable resource for scientists, aquaculture and fishery experts, sustainability enthusiasts and scholars in the areas of biology and marine agriculture.\u003c\/p\u003e","brand":"Gardners","offers":[{"title":"Default Title","offer_id":52894803001623,"sku":null,"price":17479.59,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0679\/6918\/8119\/files\/9783030161903.jpg?v=1781257995"},{"product_id":"health-information-science-9783030521097","title":"Health Information Science","description":"\u003cp\u003eThis book provides a comprehensive introduction to computational epidemiology, highlighting its major methodological paradigms throughout the development of the field while emphasizing the needs for a new paradigm shift in order to most effectively address the increasingly complex real-world challenges in disease control and prevention. Specifically, the book presents the basic concepts, related computational models, and tools that are useful for characterizing disease transmission dynamics with respect to a heterogeneous host population. In addition, it shows how to develop and apply computational methods to tackle the challenges involved in population-level intervention, such as prioritized vaccine allocation. A unique feature of this book is that its examination on the issues of vaccination decision-making is not confined only to the question of how to develop strategic policies on prioritized interventions, as it further approaches the issues from the perspective of individuals, offering a well integrated cost-benefit and social-influence account for voluntary vaccination decisions. One of the most important contributions of this book lies in it offers a blueprint on a novel methodological paradigm in epidemiology, namely, systems epidemiology, with detailed systems modeling principles, as well as practical steps and real-world examples, which can readily be applied in addressing future systems epidemiological challenges.The book is intended to serve as a reference book for researchers and practitioners in the fields of computer science and epidemiology. Together with the provided references on the key concepts, methods, and examples being introduced, the book can also readily be adopted as an introductory text for undergraduate and graduate courses in computational epidemiology as well as systems epidemiology, and as training materials for practitioners and field workers.\u003c\/p\u003e","brand":"Gardners","offers":[{"title":"Default Title","offer_id":52894819451159,"sku":null,"price":17479.59,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0679\/6918\/8119\/files\/9783030521097.jpg?v=1781258014"},{"product_id":"eaispringer-innovations-in-communication-and-computing-9783030164508","title":"EAI\/Springer Innovations in Communication and Computing","description":"\u003cp\u003eThis book provides an insight into recent technological trends and innovations in mobility solutions and platforms to improve mobility of visually impaired people. The authors' goal is to help to contribute to the social and societal inclusion of the visually impaired. The book's topics include, but are not limited to, obstacle detection systems, indoor and outdoor navigation, transportation sustainability systems, and hardware\/devices to aid visually impaired people. The book has a strong focus on practical applications, tested in a real environment. Applications include city halls, municipalities, and companies that can keep up to date with recent trends in platforms, methodologies and technologies to promote urban mobility. Also discussed are broader realms including education, health, electronics, tourism, and transportation. Contributors include a variety of researchers and practitioners around the world.Features practical, tested applications of technological mobility solutions for visual impaired people;Presents topics such as obstacle detection systems, urban mobility, smart home services, and ambient assisted living;Includes a number of application examples in education, health, electronics, tourism, and transportation.\u003c\/p\u003e","brand":"Gardners","offers":[{"title":"Default Title","offer_id":52894822695191,"sku":null,"price":12080.49,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0679\/6918\/8119\/files\/9783030164508.jpg?v=1781258021"},{"product_id":"medicine-9783030587215","title":"Medicine","description":"\u003cp\u003eThis 5th edition of this essential textbook continues to meet the growing demand of practitioners, researchers, educators, and students for a comprehensive introduction to key topics in biomedical informatics and the underlying scientific issues that sit at the intersection of biomedical science, patient care, public health and information technology (IT). Emphasizing the conceptual basis of the field rather than technical details, it provides the tools for study required for readers to comprehend, assess, and utilize biomedical informatics and health IT. It focuses on practical examples, a guide to additional literature, chapter summaries and a comprehensive glossary with concise definitions of recurring terms for self-study or classroom use.Biomedical Informatics: Computer Applications in Health Care and Biomedicine reflects the remarkable changes in both computing and health care that continue to occur and the exploding interest in the role that IT must play in carecoordination and the melding of genomics with innovations in clinical practice and treatment.  New and heavily revised chapters have been introduced on human-computer interaction, mHealth, personal health informatics and precision medicine, while the structure of the other chapters has undergone extensive revisions to reflect the developments in the area. The organization and philosophy remain unchanged, focusing on the science of information and knowledge management, and the role of computers and communications in modern biomedical research, health and health care.\u003c\/p\u003e","brand":"Gardners","offers":[{"title":"Default Title","offer_id":52894842552599,"sku":null,"price":13430.27,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0679\/6918\/8119\/files\/9783030587215.jpg?v=1781258042"},{"product_id":"anticipatory-ethics-and-the-use-of-crispr-in-humans-9783030983680","title":"Anticipatory Ethics and The Use of CRISPR in Humans","description":"\u003cp\u003eThe future of gene editing in humans will involve the use of CRISPR. How we think about the combination of the scientific, ethical, and moral aspects of this technology is paramount to the success or failure of CRISPR in humans. Unfortunately, the current scientific discussion around CRISPR in humans has left ethics trailing behind due to the rapid pace of innovation. New modes of ethics and stakeholder participation are needed to keep pace with rapid scientific advances and provide the necessary policy and ethical frameworks necessary to help CRISPR flourish as an important health care tool to treat human disease. This requires intense interdisciplinary collaboration and discussion between scientists and philosophers, policymakers and legal scholars, and the public.Dr. Michael W. Nestor (a neuroscientist who actively uses CRISPR in pre-clinical research) and Professor Richard Wilson (a philosopher who focuses on anticipatory ethics) set out to develop a new ethical approachconsidering the use of CRISPR in human targeted therapies. The field of anticipatory ethics is uniquely poised to tackle questions in fast-evolving technical areas where the pace of innovation outstrips traditional philosophical approaches. Furthermore, because of its \u0026amp;quote;anticipatory\u0026amp;quote; nature, this type of analysis provides the opportunity to look ahead and into the future concerning potential uses of CRISPR in humans, uses that are not currently possible. Nestor and Wilson collaborate both scientifically and philosophically in this book to forecast potential outcomes as the scientific and medical community goes beyond using CRISPR to correct genes that underlie diseases where a single gene is involved. Instead, Nestor and Wilson envision CRISPR in complex, multigenic disorders with a specific focus on the use of CRISPR to edit genes involved in mental traits like IQ or other cognitive characteristics. They argue that the use of CRISPR to modify genes that are potentially important for mental traits represents a particular category for special consideration from scientists, policymakers, the public, and other stakeholders.  Nestor and Wilson explain why using CRISPR to alter mental states is very different from treating a disease like cancer by combining the latest scientific advancements with anticipatory ethics and philosophical phenomenology. Their analysis considers the role that mental states play in personhood and the lived experience-as genes that can change mental\/cognitive attributes like IQ have wide-ranging effects on the lived experience in ways that are categorically different from other attributes. This book was written to set a non-exhaustive framework for shared understanding and discussion across disciplines and appeal to scientists and non-scientists alike. This appeal is made inclusively, inviting all stakeholders to engage in active dialogue about the appropriate context for using CRISPRand other gene-editing technologies in humans. It provides policy analysis and recommendations for assuring the most inclusive, equitable, and ethically sound use of CRISPR in humans, concerning its positive potential to treat mental conditions like depression, schizophrenia, Alzheimer's disease, autism, and the potential to induce other cognitive enhancements.\u003c\/p\u003e","brand":"Gardners","offers":[{"title":"Default Title","offer_id":52894887313687,"sku":null,"price":14780.04,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0679\/6918\/8119\/files\/9783030983680.jpg?v=1781258189"},{"product_id":"advances-in-experimental-medicine-and-biology-9783031237058","title":"Advances in Experimental Medicine and Biology","description":"\u003cp\u003eThis book aims to gather the current knowledge regarding different aspects of brain and spinal cord tumors in order to more efficiently help the patients. Brain tumors comprise about 5-9% of all human neoplasms; and the central nervous system (CNS) neoplasms are ranked among the most prevalent neoplasms of childhood as well. The more we know about the nature and characteristic of brain and spinal cord tumors, the more precise decision could be made for each patient, in order to reach the best outcome. While surgical resection, chemotherapy, and radiotherapy have been considered as the standards of care for benign and\/or malignant CNS tumors since a long time ago, new therapeutic approaches such as immunotherapy have been recently proposed to be considered for treatment of CNS tumors, especially as in some cases, the tumors might be inoperable or the patient may not benefit from other treatment modalities after several recurrences.The second volume of the book focuses on clinical aspects of these tumors. Accordingly, the most important brain and spinal cord tumors are specifically discussed in each chapter based on a rational outlining for all chapter in this volume: Background and epidemiology, genetics, immunology and molecular biology, histopathology and morphology, imaging and radiologic features, clinical manifestations, therapeutic approaches, surgical intervention, chemotherapy and radiotherapy, new therapeutic modalities, follow-up, and prognosis. The chapters of this volume discuss the following pathologies of brain and spinal cord tumors: malignant glioma, benign glioma, meningiomas and other meningeal tumors, ependymomas, medulloblastomas, pineal tumors, choroid plexus and ventricular tumors, neuroectodermal tumors of CNS, neuroepithelial tumors of CNS, pituitary gland tumors, craniopharyngioma, schwannomas and nerve-sheet tumors, hemangioblastomas and other vascular originating tumors, brain and spinal tumors of embryonic origin, germ line cell tumors, malignant bone or cartilage-originating tumors of brain and spine, benign bone or cartilage-originating tumors of brain and spine, brain tumors affecting the orbit globe and orbit tumors affecting the brain, CNS lymphomas, metastatic lesions of the brain and spine, malignant spinal tumors, benign spinal tumors, brain and\/or spinal cord tumors accompanied with other diseases or syndromes, psychological and psychiatric aspects of brain and spinal cord tumors, a brief explanation on surgical approaches for treatment of different brain tumors. This volume of book is useful for physicians of different specialties, mainly neurosurgeons, neurologists, neuropathologists, and neuroradiologists.\u003c\/p\u003e","brand":"Gardners","offers":[{"title":"Default Title","offer_id":52894898258199,"sku":null,"price":14846.17,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0679\/6918\/8119\/files\/9783031237058.jpg?v=1781258319"},{"product_id":"health-informatics-9783031271731","title":"Health Informatics","description":"\u003cp\u003eThis extensively revised new edition comprehensively reviews the rise of clinical research informatics (CRI). It enables the reader to develop a thorough understanding of how CRI has developed and the evolving challenges facing the biomedical informatics professional in the modern clinical research environment. Emphasis is placed on the changing role of the consumer and the need to merge clinical care delivery and research as part of a changing paradigm in global healthcare delivery. Clinical Research Informatics presents a detailed review of using informatics in the continually evolving clinical research environment. It represents a valuable textbook reference for all students and practising healthcare informatics professional looking to learn and expand their understanding of this fast-moving and increasingly important discipline.\u003c\/p\u003e","brand":"Gardners","offers":[{"title":"Default Title","offer_id":52894898553111,"sku":null,"price":8097.3,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0679\/6918\/8119\/files\/9783031271731.jpg?v=1781258327"},{"product_id":"internet-of-things-9783031086373","title":"Internet of Things","description":"\u003cp\u003eThis book presents research on how interpretable cognitive IoT can work to help with the massive amount of data in the healthcare industry. The authors give importance to IoT systems with intense machine learning features; this ensures the scope corresponds to use of cognitive IoT for understanding, reasoning, and learning from medical data. The authors discuss the interpretability of an intelligent system and its trustworthiness as a smart tool in the context of massive healthcare applications. As a whole, book combines three important topics: massive data, cognitive IoT, and interpretability. Topics include health data analytics for cognitive IoT, usability evaluation of cognitive IoT for healthcare, interpretable cognitive IoT for health robotics, and wearables in the context of IoT for healthcare. The book acts as a useful reference work for a wide audience including academicians, scientists, students, and professionals.\u003c\/p\u003e","brand":"Gardners","offers":[{"title":"Default Title","offer_id":52894898585879,"sku":null,"price":13496.4,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0679\/6918\/8119\/files\/9783031086373.jpg?v=1781258328"},{"product_id":"eaispringer-innovations-in-communication-and-computing-9783031236839","title":"EAI\/Springer Innovations in Communication and Computing","description":"\u003cp\u003eThis book contains multidisciplinary advancements in healthcare and technology through artificial intelligence (AI). The topics are crafted in such a way to cover all the areas of healthcare that require AI for further development. Some of the topics that contain algorithms and techniques are explained with the help of source code developed by the chapter contributors. The book covers the advancements in AI and healthcare from the Covid 19 pandemic and also analyzes the readiness and need for advancements in managing yet another pandemic in the future. Most of the technologies addressed in this book are added with a concept of encapsulation to obtain a cookbook for anyone who needs to reskill or upskill themselves in order to contribute to an advancement in the field. This book benefits students, professionals, and anyone from any background to learn about digital disruptions in healthcare.\u003c\/p\u003e","brand":"Gardners","offers":[{"title":"Default Title","offer_id":52894899241239,"sku":null,"price":20245.27,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0679\/6918\/8119\/files\/9783031236839.jpg?v=1781258351"},{"product_id":"translating-healthcare-through-intelligent-computational-methods-9783031277009","title":"Translating Healthcare Through Intelligent Computational Methods","description":"\u003cp\u003eThis book provides information on interdependencies of medicine and telecommunications engineering and how Covid exemplifies how the two must rely on each other to effectively function in this era. The book discusses new techniques for medical service improvisation such as clear cut views on medical technologies. The authors provide chapters on processing of medical amenities using medical images, the importance of data and information technology in medicine, and machine learning and artificial intelligence in healthcare. Authors include researchers, academics, and professionals in the field of communications engineering with a variety of perspectives.\u003c\/p\u003e","brand":"Gardners","offers":[{"title":"Default Title","offer_id":52894906188055,"sku":null,"price":21595.05,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0679\/6918\/8119\/files\/9783031277009.jpg?v=1781258409"},{"product_id":"biomedical-and-life-sciences-9783030333089","title":"Biomedical and Life Sciences","description":"\u003cp\u003eThis book explores the broad and diverse biological and physiological impacts of established and newly discovered cyclic di-nucleotide second messenger signaling systems, while also providing descriptions of the intriguing biochemical characteristics of multiple turnover enzymes and receptors. The respective chapters discuss the commonalities and diversity of cyclic di-GMP, cyclic di-AMP and recently discovered cyclic GMP-AMP signaling systems in manifold Gram-negative and Gram-positive bacteria. The global human pathogens Mycobacterium tuberculosis, Vibrio cholerae, Salmonella typhimurium, Escherichia coli and Streptococcus pneumoniae, the facultative human pathogen Pseudomonas aeruginosa, global plant pathogens as exemplified by Xanthomonas campestris and Burkholderia spp., and the omnipresent probiotic Lactobacilli, as well as environmentally importantphotoautotrophic cyanobacteria, the multicellular Myxococcus xanthus, and chemolithotrophic Acidithiobacillus are among the representatives of the microbial kingdom that are described.In turn, the various aspects of bacterial physiology affected by these signaling systems- e.g. biofilm formation and dispersal, the cell cycle, motility, virulence, production of antimicrobials, fundamental metabolism and osmohomeostasis - are discussed in detail in the context of different microorganisms. Dedicated chapters focus on the population diversity of cyclic dinucleotide signaling systems, their tendency to be horizontally transferred, the cyclic di-GMP signaling system in the social amoeba Dictyostelium, honorary cyclic (di)nucleotides, and the development of strategies for interfering with cyclic dinucleotide signaling in order to manipulate microbial behavior.Taken together, the chapters provide an authoritative source of information fora broad readership: beginners and advanced researchers from various disciplines; individuals seeking a broad overview of cyclic di-nucleotide signaling; and those who want to learn more about specific aspects. Also featuring reviews with a forward-looking perspective, the book offers a valuable source of inspiration for future research directions.\u003c\/p\u003e","brand":"Gardners","offers":[{"title":"Default Title","offer_id":52894914380055,"sku":null,"price":14780.04,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0679\/6918\/8119\/files\/9783030333089.jpg?v=1781258469"},{"product_id":"antimicrobials-in-livestock-1-regulation-science-practice-9783030467210","title":"Antimicrobials in Livestock 1: Regulation, Science, Practice","description":"\u003cp\u003eThis first volume in a two-volume work enhances readers' understanding of antimicrobial resistance mechanisms in selected bacterial species that cause diseases in major food producing animals. It provides an overview of the current legislation and policies seeking to regulate the authorisation, manufacturing, distribution and use of veterinary antimicrobials in practice in a way that helps to contain the spread of antimicrobial resistance. The focus is put on Europe, without neglecting the global context. Moreover, attention is paid to various uses of antimicrobials in livestock, considering both their risks and benefits, from the distant past to the present. Growth promotion, prophylaxis, metaphylaxis, diagnostics and treatment are discussed not only with regard to food production and animal health, but also considering the One Health concept, which combines public and animal health with environmental aspects. A summary of various systems for monitoring the use of antimicrobials is provided, as well as an overview of the diseases that European veterinarians most often treat with antimicrobials. In closing, the book addresses the complexity of recent measures that are of key importance for antimicrobial stewardship, e.g. biosecurity, vaccination and other preventive tools including the newest technologies like smart farming. The complete two-volume work provides an extensive review of various aspects related to the use of antimicrobials in veterinary medicine, especially considering major food producing species, their most common infectious diseases and causative pathogens, and mainly focusing on the situation in Europe, without ignoring the global context. While Volume I discusses more general aspects of antibiotic use such as regulatory, laboratory and practical issues from different perspectives, Volume II more specifically discusses medical aspects and the use of antimicrobials in cattle, pigs, poultry and horses, as well as pharmacokinetics and pharmacodynamics, two of the most important factors determining the success of treatment. In both volumes, each chapter confronts the reader with open questions to stimulate further discussions and future research on the topics covered.\u003c\/p\u003e","brand":"Gardners","offers":[{"title":"Default Title","offer_id":52894917230871,"sku":null,"price":18829.37,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0679\/6918\/8119\/files\/9783030467210.jpg?v=1781258511"},{"product_id":"handbook-of-experimental-pharmacology-9783031268595","title":"Handbook of Experimental Pharmacology","description":"\u003cp\u003eThis volume of the Handbook of Experimental Pharmacology, which celebrated its 100th anniversary in 2019, addresses the rapidly growing and evolving field of metabolomics. It has been compiled and designed to broaden and enrich your understanding as well as simplify a complicated picture of the diverse field of metabolomics. This is accomplished by chapters from experts in the field on basic principles as well as reviews and updates of analytical techniques. The variety and different perspectives of the NMR approaches are described in the chapters By David Wishart, Daniel Raftery and Ryan McKay, while mass spectrometry advances are covered by Charles R. Evans and Stefan Kempa. This book also reflects the state of the art in the application of metabolomics to cell biology (Marta Cascante and Ulrich Guenther) and chapters that share insights into the application of metabolomics in various diseases (Paola Turano and Claudio Luchinat, Rachel S. Kelly and Jessica Lasky-Su,Paige Lacy, and Angela Rogers. Relationships of metabolomics with drugs are highlighted by Robert Verpoorte (natural products drug discovery), by Oscar Millet and by Turano and Luchinat (perspectives in precision medicine) and by Daniel L. Hertz (drug-induced peripheral neuropathy). 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